Heather Pavilion East 452D
2733 Heather Street
Vancouver, BC V5Z 3J5
Canada
Contact Info
work phone: 6048754588
work fax: 6048754013
Position(s)
Clinical Assistant Professor, Division of Infectious Diseases
Clinical Investigator, Mahidol Oxford Tropical Medicine Research Unit
Co-director, UBC Tropical ans Geographic Medicine Intensive Short Course
Education
University of Oxford, DPhil in Clinical Medicine
University of British Columbia, Infectious Diseases Fellowship, FRCPC
University of Liverpool, DTMH
University of British Columbia, Internal Medicine Residency, FRCPC
University of Calgary, MD
University of Calgary, MSc
University of Calgary, BSc
Research interests

·       Malaria pathophysiology and treatment of severe malaria

Tropical Medicine

 

·  

Publications

Ndour PA, Larréché S, Mouri O, Argy N, Gay F, Roussel C, Jauréguiberry S, Perillaud C, Langui D, Biligui S, Chartrel N, Mérens A, Kendjo E, Ghose A, Hassan MMU, Hossain MA, Kingston HWF, Plewes K, Dondorp AM, Danis M, Houzé S, Bonnefoy S, Thellier M, Woodrow CJ, Buffet PA; French Artesunate Working Group. Measuring the Plasmodium falciparum HRP2 protein in blood from artesunate-treated malaria patients predicts post-artesunate delayed hemolysis.  Sci Transl Med 2017; 5;9(397).

Plewes K, Soontarawirat I, Ghose A, Bancone G, Kingston HWF, Herdman MT, Leopold SJ, Ishioka H, Faiz MA, Anstey NM, Day NPJ, Hossain MA, Imwong M, Dondorp AM, Woodrow CJ. Genotypic and phenotypic characterization of G6PD deficiency in Bengali adults with severe and uncomplicated malaria. Malar J 2017;16(1):134.

 

Plewes K, Kingston HW, Ghose A, Maude RJ, Herdman MT, Hasan, MU, Haider MS, Alam S, Piera K, Charunwatthana P, Yeo TW, Lee SJ, Turner GDH, Faiz MA, Anstey NM, Roberts LJ, White NJ, Day NPJ, Hossain A, Dondorp AM. Cell-free hemoglobin mediated oxidative stress is associated with acute kidney injury and renal replacement therapy in severe falciparum malaria: an observational study. BMC Infect Dis 2017; 17(1):313.

 

Jeeyapant A, Kingston HW, Plewes K, Maude RJ, Hanson J, Herdman MT, Leopold SJ, Ngernseng T, Charunwatthana P, Phu NH, Ghose A, Hasan MM, Fanello CI, Faiz MA, Hien TT, Day NP, White NJ, Dondorp AM. Defining Surrogate endpoints for clinical trials in severe falciparum malaria. PLoS One 2017; 12(1)

Ishioka H, Ghose A, Charunwatthana P, Maude R, Plewes K, Kingston H, Intharabut B, Woodrow C, Chotivanich K, Sayeed AA, Hasan MU, Day NP, Faiz MA, White NJ, Hossain A, Dondorp AM. Sequestration and red cell deformability as determinants of hyperlactataemia in falciparum malaria. J Infect Dis 2016; 19(1):382.

Plewes K, Maude RJ, Ghose A, Dondorp AM. Severe falciparum malaria complicated by prolonged haemolysis and rhinomaxillary mucormycosis after parasite clearance: a case report. BMC Infect Dis 2015; 15(1):555.

Plewes K, Haider MS, Kingston HW, Yeo TW, Ghose A, Hossain MA, Dondorp AM, Turner GDH, Anstey NM. Severe falciparum malaria treated with artesunate complicated by delayed onset haemolysis and acute kidney injury. Malar J 2015; 14:246.

Hanson J, Phu NH, Hasan MU, Charunwatthana P, Plewes K, Maude RJ, Prapansilp P, Kingston HW, Mishra SK,   Mohanty S, Price RN, Faiz MA, Dondorp AM, White NJ, Hien TT, Day NPJ. The clinical implications of thrombocytopenia in adults with severe falciparum malaria: a retrospective analysis. BMC Med 2015;13(1): 97.

Tun KM, Imwong M, Lwin KM, Win AA, Hlaing, TM, Hlaing T, Lin K, Kyaw MP, Plewes K, Faiz MA, Dhorda M, Cheah PY, Pukrittayakamee S, Ashley EA, Anderson TJ, Nair S, McDew-White M, Flegg JA, Grist EP, Guerin P, Maude RJ, Smithius F, Dondorp AM, Day NP, Nosten F, White NJ, Woodrow CJ. Spread of artemisinin-resistant Plasmodium falciparum in Myanmar: as cross-sectional survey of the K13 molecular marker. Lancet Infect Dis 2015; 15(4):415-421.

Plewes K, Royakkers AA, Hanson J, Hasan MMU, Alam S, Ghose A, Maude RJ, Stassen PM, Prakaykaew C, Lee SJ, Turner GDH, Dondorp AM, Schultz, MJ. Correlation of biomarkers for parasite burden and immune activation with acute kidney injury in severe falciparum malaria. Malar J 2014;13:91.

Maude RJ, Silamut K, Plewes K, Charunwatthana P, Ho M, Faiz MA, Rahman R, Hossain MA, Hassan MU, Bin    Yunus E, Hoque G, Islam F, Ghose A, Hanson J, Schlatter J, Lacey R, Eastaugh A, Tarning J, Lee SJ, White NJ, Chotivanich K, Day NP, Dondorp AM. Randomised controlled trial of levamisole hydrochloride as adjunctive therapy in severe falciparum malaria with high parasitaemia. J Infect Dis 2014; 209:120-129.

Mulvey MR, Grant JM, Plewes K, Roscoe D, Boyd DA. New Delhi metallo-β-lactamase in Klebsiella and Escherichia coli, Canada. Emerg Infect Dis 2011; 17:103-6.

Maude R, Plewes K, Charunwatthana P, Faiz MA, Yunus EB, Gofranul Hoque M, Hasan MU, Hossain A, Day NPJ, White NJ, Dondorp AM. Does artesunate prolong the QT interval in patients with severe malaria? Am J Trop Med Hyg 2009; 80(1):126–132.

Plewes K, Lee T, Maelanakhiri L, Myo M, Carrara VI, Nosten F, McGready R. Low rate of HIV and syphilis in pregnant women in refugee camps on the Thai-Burma border. Int J STD AIDS 2008; 19:833-7

 

Plewes KA, Barr SD, Gedamu L. Iron superoxide dismutases targeted to glycosomes of Leishmania chagasi are important for survival. Infect Immun 2003; 71: 5910- 20.